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BIDIRECTIONAL REPLICATION

  1. Replication which proceeds in both the directions from the point of origin is called ‘Bidirectional replication’.
  2. The replication begins by denaturation of ds-DNA at specific sites called origin.
  3. The two strands move slightly apart producing a replication bubble.
  4. In bidirectional replication, the replication starts on both the strand, in 5’ → 3’ direction on one and 3’→ 5’ direction on the other.
  5. One of the advantages of bidirectional replication is the origin is completely duplicated before replication is completed.
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