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When normal cells are transformed into cancer cells they show the following characteristics:

  1. Nucleus enlarges and has an irregular outline.
  2. Number of ribosomes increase.
  3. Mitochondria are swollen and irregular shaped
  4. Nucleolus is also enlarged and has unstable number of chromosomes.
  5. Cytoskeletal actin filaments decrease due to which the cell surface protein becomes mobile.
  6. Golgi complex is poorly developed.
  7. Cytoplasm has many inclusions. E.g. eosinophilic granules in leukemia, milk droplets in mammary tumour.