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Transcription

Translation

1.

The process involving the synthesis of m-RNA from DNA is called transcription.

The process involving the decoding of the sequence of nucleotides (Codons) present in the m-RNA into the sequence of a polypeptide chain is called translation.

2.

It takes place in the nucleus.

It takes place in the cytoplasm.

3.

m-RNA is synthesized by using one of the DNA strands as the template.

Codons present on m-RNA act as templates for the synthesis of proteins.

4.

It occurs in presence of the enzyme RNA Polymerase.

It occurs in presence of the enzyme Aminoacyl t-RNA synthetase.

5.

It does not require the participation of

t-RNA, r-RNA, ribosomes and non-sense codons.

It requires the participation of

t-RNA, r-RNA, ribosomes and non-sense codons.

6.

In eukaryotes, the m-RNA formed undergoes post-transcriptional modification such as 5’ capping, 3’ Poly-A tail, splicing of introns.

The protein formed after translation undergo post-translation modifications like phosphorylation, methylation, glycosylation, sulphonation, etc.

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