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Enzymes are highly specific in their actions.

This specificity is due to the presence of active sites of definite size and shape over the surface of enzymes so that only specific substrates can fit into them.

This specific binding leads to the formation of enzyme-substrate (ES) complex which accounts for the high specificity of enzymes.

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Specificity of enzyme or the fact that enzymes are "specific" means that each enzyme will work on only one substrate/substance.

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